![]() ![]() Maintenance of a better DW leads to improve hemodialysis quality and QOL in these patients. Conclusion: Ideal DW is better adjusted by periodic echocardiographic measurement of the IVCD in patients undergoing chronic hemodialysis. Furthermore, the Kt/V urea value, a parameter of total urea clearance, also increased significantly in the study group. The impact of periodic echocardiographic evaluation also demonstrated a significant change in the scores of physical functioning, physical role functioning and physical component summary in the study group. Results: The scores of physical functioning, physical role functioning, general health and physical component summary showed a prominent improvement in the study group but not in the control group. Besides, the Kt/V urea value, a parameter of total urea clearance, was measured at the beginning and at the end of the study in patients of both groups. QOL was evaluated using the short form 36 questionnaire (SF-36) at the beginning and at the end of the study. IVCD (IVCDmax) and minimum IVCD (IVCDmin) after a sniff test were measured, and these values were used to determine the percent collapse: (IVCDmax. The study group included 68 patients in whom the DW were adjusted by echocardiographic measurement of the IVCD, while the control group included 51 patients in whom the DW was adjusted by the conventional method. All of the patients received the IVC diameter (IVCD) measurement by echocardiography every 2 months for 1 year. Methods: This study included 119 patients with ages ranging between 27 and 90 years (mean ± standard deviation of 58.3 ± 12.8). Adjusting DW using echocardiographic measurement of the diameter of the IVC thus may be useful in maintenance of a better QOL in patients receiving chronic hemodialysis. The size of the inferior vena cava (IVC) reflects the intravascular fluid status, and the diameter of IVC correlates indirectly with DW in these patients. Bioimpedance spectroscopy (BIS) is a useful and sensitive tool for the assessment of fluid status in clinically euvolumic nondialytic CKD patients.Background/Aims: Ideal dry weight (DW) can serve as a marker of good quality of life (QOL) in patients receiving chronic hemodialysis. Conclusions: Volume overload and malnutrition were common across the spectrum of South African CKD cohorts volume overload was associated with malnutrition, inflammation, and atherosclerosis. ![]() Lean tissue index, inflammation, and atherosclerosis were associated with volume overload. Using physical examination findings as the reference measurements for volume overload, the area under the concentration curves for BCM and IVCD measurements were 0.866 (sensitivity 82%, specificity 74%, p < 0.001) and 0.727 (sensitivity 57%, specificity 70%, p < 0.001), respectively. Results: Fluid overload and malnutrition were present in 68% and 63% of studied patients, respectively. Serum interleukin-6 (IL-6) and C-reactive protein (CRP) levels were measured as markers of inflammation. Cardiac dimension measurements, and inferior vena cava diameter (IVCD) and carotid intima media thickness were assessed by echocardiography and ultrasonography, respectively. A BCM was used to assess fluid and nutritional status. Methods: 160 participants comprising hemodialysis, peritoneal dialysis, stage 3 CKD patients, and healthy controls (40 in each group) were studied. We also evaluated the usefulness of BCM measurement in assessing volume overload. This study aimed to assess volume and nutritional status among South African CKD participants and determine the relationship between malnutrition, inflammation, atherosclerosis, and volume overload using a body composition monitor (BCM). Abstract Background: Fluid retention occurs early in chronic kidney disease (CKD) resulting in increased cardiovascular morbidity and mortality. ![]()
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